In a picturesque corner of Samarkand, in the ancient mansion belonging to the rich merchant Abram Kalantarov, built on the project of the architect E.O. Neleh in style of eclecticism at the beginning of the 20th century in 1981 the regional museum of local lore was open. The building of the museum is considered a monument of architecture and is protected by the state. All halls of the building are located vryad, forming a suite. On the first floor the exposition lighting history of development of edge since the most ancient times before the beginning of the 20th century is placed.

The Mesolith-Neolithic-eneolit - the final stages it is primitive a communal system characterize stone tools and fragments of the first modelled ceramics various to destination. The era of bronze and iron is widely illustrated with photos of rock paintings. The period from VIII to the 4th centuries B.C. is presented by pottery - cups of graceful forms and also coins. Colourfully the copy from a picture of the artist V. Kaydalov "Spitamen's Revolt" supplements an exposition.
The Kushansky period (the 4-1st century AD) which is characterized by economic raising, development of an irrigation, different types of crafts, blossoming of city life is shown by coins of Kushansky tsars.
In an exposition of the early Middle Ages - various household and ritual ceramics, the Sughd coins and elegant women's jewelry and also pieces of funeral stock, weapon (sword) from barrows Akdzhartepa, Sazagan, Agalyksay.
In the exposition devoted to gaining Sogd by Arabs copies of fine palace paintings from the ancient settlement Afrasiab, the drawing reconstruction "Sughd Soldiers", a sword and tips of the Sughd arrows are submitted to the period.
A fragment of a vessel presents the period of Islamic revival from red Egyptian glass, lyustrovy ceramics from the Iranian city of Reya, abundance of coins. Tips of the Mongolian arrows, the drawing of the Samarkand citadel ruined by Genghis Khan are presented to expositions.
The period of board Amira Temura and Temuridov is presented by materials from excavation - sets of metal wares, bones, flew down and also coins of HSh-HVI of centuries give an idea of handicraft trade, caravan trade and the commodity-money relations of an era Temuridov. Here the most rare exhibits - a war and ceremonial drum of the highest nobility of the 15-16th centuries and also the unique book De Sanctiyena the "Temur's History" published in 1678 in Amsterdam are presented.
In an exposition it is possible to see the reconstruction of observatory executed by the architect V.A. Nielsen and also photos of the remained part of the grandiose astronomical tool - a quadrant (sextant).